KAI1 Gene Is Engaged in NDRG1 Gene-mediated Metastasis Suppression through the ATF3-NFκB Complex in Human Prostate Cancer
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چکیده
منابع مشابه
Kai1 Is Engaged in Ndrg1-mediated Metastasis Suppression through Atf3-nfkb Complex in Human Prostate Cancer
KAI1 IS ENGAGED IN NDRG1-MEDIATED METASTASIS SUPPRESSION THROUGH ATF3-NFKB COMPLEX IN HUMAN PROSTATE CANCER Wen Liu, Megumi Iiizumi-Gairani, Hiroshi Okuda, Aya Kobayashi, Misako Watabe, Sudha K. Pai, Puspa R. Pandey, Fei Xing, Koji Fukuda, Vishnu Modur, Shigeru Hirota, Kazuyuki Suzuki, Toshimi Chiba, Masaki Endo, Tamotsu Sugai, and Kounosuke Watabe Department of Medical Microbiology, Immunology...
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15 صفحه اولTumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis.
Cap43 has been identified as a nickel- and calcium-induced gene, and is also known as N-myc downstream-regulated gene 1 (NDRG1), Drg-1 and rit42. It is also reported that overexpression of Cap43 suppresses metastasis of some malignancies, but its precise role remains unclear. In this study, we asked how Cap43 could modulate the tumor growth of pancreatic cancer. Stable Cap43 cDNA transfectants ...
متن کاملMolecular and Cellular Pathobiology IGFBP-3 Is a Metastasis Suppression Gene in Prostate Cancer
The insulin-like growth factor binding protein IGFBP-3 is a proapoptotic and antiangiogenic protein in prostate cancer (CaP). Epidemiologic studies suggest that low IGFBP-3 is associated with greater risk of aggressive, metastatic prostate cancers, but in vivo functional data are lacking. Here we show that mice that are genetically deficient in IGFBP-3 exhibit weaker growth of primary prostate ...
متن کاملRe: IGFBP-3 is a metastasis suppression gene in prostate cancer.
The insulin-like growth factor binding protein IGFBP-3 is a proapoptotic and antiangiogenic protein in prostate cancer (CaP). Epidemiologic studies suggest that low IGFBP-3 is associated with greater risk of aggressive, metastatic prostate cancers, but in vivo functional data are lacking. Here we show that mice that are genetically deficient in IGFBP-3 exhibit weaker growth of primary prostate ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2011
ISSN: 0021-9258
DOI: 10.1074/jbc.m111.232637